Recombinant rat Interleukin-17A
  • Recombinant rat Interleukin-17A

Recombinant rat Interleukin-17A

( 别名:Interleukin-17A; CTLA-8; CTLA 8; CTLA8; Cytotoxic T lymphocyte associated antigen 8; Cytotoxic T lymphocyte associated serine esterase 8; IL 17A; IL-17A; IL-17; Interleukin 17; Interleukin-17; Interleukin 17A; Interleukin17; Interleukin17A; IL17_HUMAN. )
货      号 SB-ZR397
规      格 100μg
品      牌 圣尔生物share-bio
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产品编号 名称 包装 品牌 目录价 促销价 货期 数量 购物车
SB-ZR397 Recombinant rat Interleukin-17A 100μg 圣尔生物share-bio ¥3800.00
SB-ZR397 Recombinant rat Interleukin-17A 1mg 圣尔生物share-bio ¥19800.00
SB-ZR397 Recombinant rat Interleukin-17A 250μg 圣尔生物share-bio ¥7800.00
SB-ZR397 Recombinant rat Interleukin-17A 25μg 圣尔生物share-bio ¥1080.00
SB-ZR397 Recombinant rat Interleukin-17A 500μg 圣尔生物share-bio ¥10800.00
SB-ZR397 Recombinant rat Interleukin-17A 5μg 圣尔生物share-bio ¥199.00

Recombinant rat Interleukin-17A 介绍

产品详情

The originally described IL-17 protein, now known as IL-17A, is a homodimer of two 1333 amino acid chains that are secreted by activated T-cells, which act on stromal cells to induce production of proinflammatory and hematopoietic bioactive molecules. Human Interleukin-17A (IL-17A) is encoded by the IL17A gene located on the chromosome 6 and belongs to the IL-17 family that contains IL-17A, IL-17B, IL-17C, IL-17D, IL-17E and IL-17F.  The six known members of this family are secreted as homodimers. Mature rat IL-17A shares 60% and 89% amino acid sequence identity with human and mouse IL-17A, respectively. IL-17A exhibits cross-species bioactivity between human and murine cells. Recombinant Rat IL-17A is a 30.0kDa, disulfide-linked homodimer of two 133 amino acid polypeptide chains.

Product Information

Product Name

Recombinant Rat Interleukin-17A

(rRtIL-17A)

Synonyms

IL-17, CTLA-8

Source

Expressed in E. coli.

Molecular weight

Approximately 30kDa, a homodimer of two 133amino acid polypeptide chains.

Accession

Q61453 Ala18-Ser150

AA Sequence

AVLIPQSSVCPNAEANNFLQNVKVNLKVINSLSSKASSRRPSDYLNRSTSPWTLSRNEDPDRYPSVIWEAQCRHQRCVNAEGKLDHHMNSVLIQQEILVLKREPEKCPFTFRVEKMLVGVGCTCVSSIVRHAS

Purity

95% by SDS-PAGE or HPLC.

Biological activity

Fully biologically active when compared to standard. The ED50 as determined by inducing IL-6 secretion of murine NIH/3T3 cells is less than 1.0ng/ml, corresponding to a specific activity of >1.0 ×106 IU/mg.

Formulation

Lyophilized from a 0.2 µm filtered concentrated solution in 20mM PB, 300mM NaCl, pH6.5

Endotoxin level

0.01EU/μg rRtIL-17A protein as determined by LAL method.

Reconstitution

Before use this product, please read the direction below carefully.

1、 This vial must be briefly centrifuged prior to opening to bring the contents to the bottom.

2、 Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. 

Stock solutions should be apportioned into working aliquots and stored at -20. Further dilutions should be made in appropriate buffered solutions.

Storage/ Stability

White lyophilized powder. For long term storage, the product should be stored -20.

36 months, -20 to -70 as supplied.

1 month, 2 to 8under sterile conditions after reconstitution;

3 months, -20 to -70 under sterile conditions after reconstitution.

Please avoid repeated freeze-thaw cycles.

THIS PRODUCT IS FOR RESEARCH, LABORATORY AND EVALUATION PURPOSE ONLY.

 

储存条件及期限 冻干粉于-20℃到-80℃长期保存3年,溶液状态保存期3个月,避免反复冻融。
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Recombinant rat Interleukin-17A 说明书

For research use only. Not intended for human and animal therapeutic or diagnostic use.

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