rAPi-M1 (Phospholipase A2)
  • rAPi-M1 (Phospholipase A2)

rAPi-M1 (Phospholipase A2)

( 别名:PA2GA_HUMAN; Phospholipase A2, membrane associated; EC:3.1.1.4; GIIC sPLA2; Group IIA phospholipase A2; Non-pancreatic secretory phospholipase A2 (NPS-PLA2); Phosphatidylcholine 2-acylhydrolase 2A; PLA2B; PLA2L; RASF-A; phospholipase A2 group IIA; MOM1; PLA2; PLA2S; PLAS1; sPLA2; )
货      号 SB-ZR098
规      格 100μg
品      牌 圣尔生物share-bio
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产品编号 名称 包装 品牌 目录价 促销价 货期 数量 购物车
SB-ZR098 rAPi-M1 (Phospholipase A2) 100μg 圣尔生物share-bio ¥2180.00
SB-ZR098 rAPi-M1 (Phospholipase A2) 10μg 圣尔生物share-bio ¥199.00
SB-ZR098 rAPi-M1 (Phospholipase A2) 1mg 圣尔生物share-bio ¥18600.00
SB-ZR098 rAPi-M1 (Phospholipase A2) 500μg 圣尔生物share-bio ¥10800.00
SB-ZR098 rAPi-M1 (Phospholipase A2) 50μg 圣尔生物share-bio ¥1180.00

rAPi-M1 (Phospholipase A2) 介绍

产品详情

Api m1, a glycoprotein of the phospholipase 2 (PLA2) family, is a major allergen of Apis mellifera (honeybee) venom (HBV) and a marker allergen for genuine sensitization to this venom. Api m 1 contributes 12-16% of venom dry weight. Api m 1 is consistently found as a major allergen in HBV-allergic patients. Of the 12 known allergens within HBV, Api m 1 is considered the most prominent allergen, in terms of prevalence of sensitization, levels of specific IgE to Api m 1, and quantitative correlation between Api m 1 and HBV specific IgE. Api m 1 does not cross-react with phospholipases of the PLA1 family found in Vespid venoms, therefore, Api m 1 is a marker allergen allowing to discriminate between HBV and Vespid venom sensitization. Recombinant Api m1 is a 15.2kDa globular protein containing 134 amino acid residues.

Product Information

Product Name

Recombinant Apis mellifera Phospholipase A2/Api m1

(rApi m1)

Synonyms

PLA2

Source

Expressed in E. coli.

Molecular weight

Approximately 15.2kDa, a single non-glycosylated polypeptide chain containing 134 amino acids.

Accession

P00630 Ile34-Tyr167 

AA Sequence

IIYPGTLWCGHGNKSSGPNELGRFKHTDACCRTHDMCPDVMSAGESKHGLTNTASHTRLSCDCDDKFYDCLKNSADTISSYFVGKMYFNLIDTKCYKLEHPVTGCGERTEGRCLHYTVDKSKPKVYQWFDLRKY

Purity

97% by SDS-PAGE or HPLC.

Biological activity

Strong Reactivity to honeybee stung positive serum by IGEs test

Formulation

Lyophilized from a 0.2µm filtered concentrated solution in 20mM PB, 150mM NaCl, pH7.4.

Endotoxin level

0.01EU/μg rApi m1 protein as determined by LAL method.

Reconstitution

Before use this product, please read the direction below carefully.

1、 This vial must be briefly centrifuged prior to opening to bring the contents to the bottom.

Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.

Storage/ Stability

For long term storage, the product should be stored -20 

36 months, -20 to -70 as supplied.

1 month, 2 to 8 under sterile conditions after reconstitution;

3 months, -20 to -70 under sterile conditions after reconstitution.

Please avoid repeated freeze-thaw cycles.

THIS PRODUCT IS FOR RESEARCH, LABORATORY AND EVALUATION PURPOSE ONLY.

 

储存条件及期限 冻干粉于-20℃到-80℃长期保存3年,溶液状态保存期3个月,避免反复冻融。
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rAPi-M1 (Phospholipase A2) 说明书

For research use only. Not intended for human and animal therapeutic or diagnostic use.

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